Loss of gut integrity is linked to various human diseases including inflammatory bowel disease.However, the mechanisms that lead to loss of barrier function remain poorly understood.Using D.melanogaster, we demonstrate that dietary restriction (DR) slows the age-related decline in intestinal integrity by enhancing enterocyte cellular fitness throug
Subacute Sclerosing Panencephalitis (SSPE) el reformador tequila anejo is a rare, slowly progressive disorder that affects the entire nervous system.It primarily involves the cerebral cortex, subcortex and optic nerves.Caused by a mutated strain of the measles virus, the disease is mostly irreversible and devastating.It presents with gradually prog
Dendritic cells (DCs) are endowed with a unique potency to prime T cells, as well as to orchestrate their expansion, functional polarization and effector activity in non-lymphoid tissues or in their draining lymph nodes.The concept of harnessing DC immunogenicity to induce protective responses in cancer patients was put forward about 25 years ago a
Abstract We investigate the subleading-power corrections to the exclusive B → Dℓν ℓ form factors at O $$ mathcal{O} $$ ( α s 0 $$ {alpha}_s^0 $$ ) in the light-cone sum rules here (LCSR) framework by including the two- and three-particle higher-twist contributions from the B-meson light-cone distribution amplitudes up to the twist-six accur
Rhizobia can establish mutually beneficial interactions with legume plants by colonizing their roots to induce the formation of a specialized structure known as a nodule, inside of which the bacteria are able to fix atmospheric nitrogen.It is yale law school colors well established that the compatibility of such interactions is mainly determined by